Gallbladder benign Pyloric gland adenoma 胆囊良性幽门腺瘤
Definition / general 定义
Grossly visible, noninvasive neoplasm of the gallbladder composed of uniform back to back mucinous glands arranged in a tubular configuration
肉眼可见，非浸润性胆囊肿瘤，由排列成管状的均匀背对背黏液腺组成
WHO Classification of Tumours Editorial Board: WHO Classification of Tumours – Digestive System Tumours (Medicine), 5th Edition, 2019
Architecture is often complex Glands are bland looking pyloric type or Brunner gland-like
其结构通常复杂，较白，看上去和幽门腺和Brunner腺样类似
There is minimal cytological atypical in most of the lesion
大部分病变细胞异型性小
Low grade dysplasia is not a required diagnostic criterion
低度异型增生不是必要的诊断标准
Foci of high grade dysplasia can be seen in larger specimens
在较大的标本中能看到高度异型增生的病灶
If lesion is > 1 cm with dysplasia present, classification as intracholecystic papillary (tubular) neoplasm is recommended by some authors
如果病变大于1cm，且存在异型增生，一些作者建议将其分类为胆囊内乳头状（管状）肿瘤
Essential features
Grossly visible, complex, back to back uniform mucinous glands of pyloric type of Brunner glands
Usually > 0.5 cm and < 2cm
< 0.5 cm arising in a background of pyloric gland metaplasia in the adjacent mucosa should not be designated as pyloric gland adenoma
> 1 cm with dysplasia may be classified as intracholecystic papillary (tubular) neoplasm