鳞化，有无穿刺病史

@周泉 无手术及穿刺病史

没有病史也可以有鳞化

我觉得生长方式好像不是很好，但细胞异型性不明显

Squamous Metaplasia

Squamous metaplasia is a benign process whereby the follicular cells change and acquire features of squamous epithelium. It occurs in a wide variety of situations. Squamous metaplasia is most common with chronic lymphocytic thyroiditis of Hashimoto’s type and nodular goiters with retrogressive changes. Squamous metaplasia is also encountered in thyroids subjected to fine needle aspiration biopsies, in the vicinity of the needle track. Among the neoplasms, squamous metaplasia is seen in papillary carcinomas (20% to 40%) either of the conventional type or of the diffuse sclerosing type and cribriform morular types.

Histologically and cytologically, squamous metaplasia appears as nests of round-to -oval cells often appearing as “morulae”. The metaplastic squamous cells are characteristically arranged in whorls. The squamous cells have abundant cytoplasm with low N/C ratios; keratinization and intercellular bridges may occasionally be seen. The nuclei are uniform with a bland chromatin pattern. Metaplastic squamous cells often assume a spindle shape, appearing elongated. They usually contain nuclei with a bland chromatin pattern.